Document Detail


Serological abnormalities in juvenile chronic arthritis: a review of 46 cases.
MedLine Citation:
PMID:  6966908     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Data of 46 patients with juvenile chronic arthritis were evaluated. All of them were under the age of 16 at the time of study. Patients with juvenile ankylosing spondylitis, psoriatic arthritis, and arthritis associated with inflammatory bowel disease were excluded from this series. Twenty-six patients had pauciarticular, 9 had systemic, 8 had polyarticular, and 3 patients had seropositive 'adult type' JCA. In all patient groups IgG, IgM, IgA, and C3 levels were significantly higher than in the control group. None of the controls but 13 of 46 patients had high IgE levels. IgA and IgG values were significantly higher in the seropositive subgroup than in the pauciarticular subgroup. There was no other positive correlation between levels of immunoglobulins, C3, and clinical features of disease. Platelet counts were significantly higher in patients with active disease. In the control group 4 out of 10 children had 'hidden' rheumatoid factor. All these children with positive findings were young.
Authors:
Z Balogh; K Merétey; A Falus; S Bozsóky
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of the rheumatic diseases     Volume:  39     ISSN:  0003-4967     ISO Abbreviation:  Ann. Rheum. Dis.     Publication Date:  1980 Apr 
Date Detail:
Created Date:  1980-08-28     Completed Date:  1980-08-28     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372355     Medline TA:  Ann Rheum Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  129-34     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Antibodies, Antinuclear / analysis
Antigen-Antibody Complex
Arthritis, Juvenile Rheumatoid / blood,  immunology*
Child
Child, Preschool
Complement C3 / analysis
Female
Humans
Immunoglobulins / analysis
Male
Platelet Count
Rheumatoid Factor / analysis
Chemical
Reg. No./Substance:
0/Antibodies, Antinuclear; 0/Antigen-Antibody Complex; 0/Complement C3; 0/Immunoglobulins; 9009-79-4/Rheumatoid Factor
Comments/Corrections

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