Document Detail


Serologic evidence of prior chlamydial infection in patients with tubal ectopic pregnancy and contralateral tubal disease.
MedLine Citation:
PMID:  3792565     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Oviductal damage from infectious salpingitis is a principle cause of ectopic pregnancy. To examine the role of Chlamydia trachomatis in patients with ectopic pregnancy, 24 patients undergoing laparotomy for ectopic pregnancy were evaluated by assessment of chlamydial serology and chlamydial cultures of tubal biopsy specimens. The patients were divided into two groups based on the presence or absence of gross abnormalities in the fallopian tube contralateral to the ectopic gestation. Ten patients in group I showed gross evidence of chronic salpingitis in the contralateral tube; 14 patients in group II had normal-appearing contralateral tubes. Chlamydial cultures were negative in both groups. Chlamydial immunoglobulin M antibodies assayed by indirect microimmunofluorescence were negative in both groups (less than or equal to 1:32). Mean geometric immunoglobulin G titers for C. trachomatis were significantly higher in the patients with evidence of contralateral chronic salpingitis (78.9 versus 13.1). These findings suggest that C. trachomatis may be a major cause of oviductal damage, which predisposes to ectopic pregnancy.
Authors:
S L Hartford; P D Silva; G S diZerega; M L Yonekura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  47     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1987 Jan 
Date Detail:
Created Date:  1987-02-19     Completed Date:  1987-02-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  118-21     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Chlamydia Infections / complications*,  diagnosis
Chlamydia trachomatis
Female
Humans
Pregnancy
Pregnancy, Tubal / etiology*
Salpingitis / etiology*
Serologic Tests

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