Document Detail


Seroepidemiology of Fasciola Hepatica in Mersin province and surrounding towns and the role of family history of the Fascioliasis in the transmission of the parasite.
MedLine Citation:
PMID:  19821202     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND/AIMS: Fascioliasis is an important zoonotic disease caused by Fasciola hepatica. This zoonosis may cause serious morbidity and a considerable financial burden. Knowledge about Fasciola hepatica and interest in this parasite have increased in Turkey recently. However, there have been few studies on the real prevalence of this condition in the country. Therefore, we aimed to determine the prevalence of fascioliasis and the role of family history of the condition in the transmission of the parasite in the province of Mersin. METHODS: Taking account of their populations, 729 people without a family history of fascioliasis and 155 people with a family history of fascioliasis from the city of Mersin and randomly selected three towns were included into the study to obtain a sample that well represented the population of the province of Mersin. A questionnaire composed of items about consumption of green leafy vegetables, stock-breeding and clinical symptoms of the disease was used to collect data. Excretory/ secretory (ES)-ELISA was used to detect IgG antibodies to Fasciola hepatica. People seropositive for Fasciola hepatica underwent abdominal ultrasonography, physical examination, biochemistry, and stool tests for the detection of Fasciola hepatica eggs. RESULTS: A total of 0.79% of the participants were seropositive for Fasciola hepatica. One point ninety-three percent of the individuals with a family history of fascioliasis and 0.55% of the individuals without a family history of fascioliasis were seropositive for Fasciola hepatica. Out of 7 individuals found to be seropositive for Fasciola hepatica, 5 were female, 2 were male, and 4 had a family history of fascioliasis. Five and 4 patients, respectively, had a history of consuming green leafy vegetables and 4 had a history of stock-breeding. The clinical evaluation revealed that 4 patients had at least one sign of fascioliasis. Three patients had signs of fascioliasis on ultrasonography and 1 had Fasciola hepatica egg in stool examination. There was no significant difference in seropositivity for Fasciola hepatica between the individuals with and without a family history of fascioliasis (x2: 0.077, p>0.05). CONCLUSIONS: The prevalence of fascioliasis was hypoendemic in the province of Mersin. There were no significant differences in the Fasciola hepatica prevalence between the groups with and without family history of fascioliasis. However, studies with larger sample sizes may reveal a difference.
Authors:
Hakan Ozturhan; G??rol Emekda??; Orhan Sezgin; Metin Korkmaz; Engin Altinta??
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology     Volume:  20     ISSN:  1300-4948     ISO Abbreviation:  Turk J Gastroenterol     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-10-12     Completed Date:  2010-01-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9515841     Medline TA:  Turk J Gastroenterol     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  198-203     Citation Subset:  IM    
Affiliation:
Departments of Microbiology, Mersin University, School of Medicine, Mersin. hakanozturhan@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Animals
Animals, Domestic
Endemic Diseases / statistics & numerical data*
Family Health
Fasciola hepatica*
Fascioliasis / epidemiology*,  transmission*,  ultrasonography
Female
Humans
Male
Middle Aged
Risk Factors
Seroepidemiologic Studies
Turkey / epidemiology
Urban Population / statistics & numerical data
Vegetables
Young Adult
Zoonoses / epidemiology*

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