Document Detail


Sero-prevalence of Taenia solium cysticercosis and Taenia solium taeniasis in California, USA.
MedLine Citation:
PMID:  15644066     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: Taenia solium Cysticercosis is a leading cause of epilepsy and neurological disability in the developing world. It is caused by ingestion of the eggs of the tapeworm, T. solium Taeniasis. The prevalence of either T. solium Cysticercosis or T. solium Taeniasis in the United States in populations at risk is poorly understood. The primary objectives of this study are to perform the first study of the sero-prevalence of T. solium Cysticercosis and T. solium Taeniasis in an at-risk community in the USA, specifically rural Southern California; identify T. solium Taeniasis positive individuals, and treat positive individuals for the tapeworm T. solium Taeniasis. METHODS: Community based sero-prevalence study of antibodies to T. solium Cysticercosis and T. solium Taeniasis in 449 subjects living in a federally funded, predominantly Hispanic residential community; and in two migrant farm worker camps in rural Ventura County, California, USA. For this study, fingerstick blood samples were obtained. Serum immunoblots for both T. solium Cysticercosis and T. solium Taeniasis were performed. RESULTS: The sero-prevalence of T. solium Cysticercosis was 1.8% and the sero-prevalence of T. solium Taeniasis by serum immunoblot was 1.1%. Taenia solium Cysticercosis and T. solium Taeniasis antibodies were not detected in children. The sero-prevalence of T. solium Taeniasis was highest in the migrant farm worker community. Handwashing frequency was correlated with T. solium Taeniasis sero-positivity. CONCLUSION: The sero-prevalence of T. solium Cysticercosis and T. solium Taeniasis in this population, as detected by serum immunoblot, approximates the prevalence in some endemic areas of Latin America. Importantly, most patients likely had prior exposure, not active infection. This study establishes for the first time, the relative sero-prevalence of T. solium Cysticercosis and T. solium Taeniasis in at-risk populations in the United States.
Authors:
C DeGiorgio; S Pietsch-Escueta; V Tsang; G Corral-Leyva; L Ng; M T Medina; S Astudillo; N Padilla; P Leyva; L Martinez; J Noh; M Levine; R del Villasenor; F Sorvillo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  111     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-01-12     Completed Date:  2005-03-29     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  84-8     Citation Subset:  IM    
Affiliation:
Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA. cmd@mednet.ucla.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Antibodies, Helminth / blood
California / epidemiology
Child
Child, Preschool
Cysticercosis / diagnosis,  epidemiology*
Female
Hispanic Americans
Humans
Infant
Male
Middle Aged
Rural Health
Seroepidemiologic Studies
Taenia solium* / immunology
Taeniasis / diagnosis,  epidemiology*
Transients and Migrants
Grant Support
ID/Acronym/Agency:
CDC 000163811/DC/NIDCD NIH HHS
Chemical
Reg. No./Substance:
0/Antibodies, Helminth

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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