Document Detail


Serious community-acquired paediatric infections in rural Asia (Bohol Island, Philippines): bacterial meningitis in children less than 5 years of age.
MedLine Citation:
PMID:  17852943     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This paper describes the clinical profile and aetiology of bacterial meningitis in infants and children less than 5 y old admitted to a rural general hospital in the Philippines. A total of 989 infants and children 0-59 months old with suspected meningitis using a standardized guideline based on clinical signs and symptoms were prospectively enrolled from April 1994 to May 2000. Blood and CSF were drawn on admission for culture, antigen testing and cell count. All had blood cultures and 623 (63%) had CSF samples. Bacterial aetiology was found in 54 (5%). The most common bacterial pathogens were H. influenzae type b (Hib) (20, 37%) and S. pneumoniae (Pnc) (10, 18%). All of the Hib infections and 8 (80%) Pnc infections were in infants less than 1 y old. 12 (22%) of the subjects with bacterial meningitis died. All strains of S. pneumoniae and H. influenzae were sensitive to chloramphenicol, cotrimoxazole and ampicillin. In conclusion, S. pneumoniae and H. influenzae type b are the most common aetiological agents of bacterial meningitis in a rural area in the Philippines, and occur especially in infants less than 1 y old. Aetiological agents were susceptible to the currently recommended antimicrobial agents.
Authors:
Erma Abucejo-Ladesma; Eric A F Simoes; Socorro P Lupisan; Lydia T Sombrero; Beatriz P Quiambao; Lorena S Gozum; Elja Herva; Petri Ruutu;
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-06-21
Journal Detail:
Title:  Scandinavian journal of infectious diseases     Volume:  39     ISSN:  0036-5548     ISO Abbreviation:  Scand. J. Infect. Dis.     Publication Date:  2007  
Date Detail:
Created Date:  2007-11-22     Completed Date:  2008-03-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0215333     Medline TA:  Scand J Infect Dis     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  983-9     Citation Subset:  IM    
Affiliation:
From the Celestino Gallares Memorial Hospital, Bohol, Philippines.
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MeSH Terms
Descriptor/Qualifier:
Age Distribution
Anti-Bacterial Agents / therapeutic use
Child, Preschool
Community-Acquired Infections / epidemiology*
Humans
Infant
Infant, Newborn
Meningitis, Bacterial / drug therapy,  epidemiology*
Philippines / epidemiology
Seasons
Time Factors
Treatment Outcome
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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