Document Detail

Serious bacterial infections in infants who have experienced an apparent life-threatening event.
MedLine Citation:
PMID:  19185390     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVE: We determine the incidence of serious bacterial infection in infants presenting to the emergency department (ED) with an apparent life-threatening event. METHODS: This was a prospective cohort study of infants younger than 12 months who were treated at an urban children's hospital ED during 1 year and who met standard criteria for an apparent life-threatening event. Sociodemographic data, presenting features, diagnostic testing, hospital course, and final diagnosis were collected. Follow-up information was obtained 4 weeks after the visit. RESULTS: Of the 198 infants enrolled, 44 (22.2%) had evaluation for serious bacterial infection: urine culture 36 (18%), blood culture 38 (19%) and cerebrospinal fluid culture 18 (9%). No infant (0/198; 95% confidence interval 0% to 1.8%) was found to have bacteremia, urinary tract infection, or bacterial meningitis, which was confirmed at the 4-week interview (99% ascertainment). Two infants were found to have enteroviral meningitis. CONCLUSION: The incidence of serious bacterial infection in this cohort was extremely low. Infants presenting with an apparent life-threatening event need not be subjected to a full serious bacterial infection evaluation routinely.
Manoj K Mittal; Frances S Shofer; Jill M Baren
Publication Detail:
Type:  Journal Article     Date:  2009-01-29
Journal Detail:
Title:  Annals of emergency medicine     Volume:  54     ISSN:  1097-6760     ISO Abbreviation:  Ann Emerg Med     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-22     Completed Date:  2009-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8002646     Medline TA:  Ann Emerg Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  523-7     Citation Subset:  AIM; IM    
Division of Emergency Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4399, USA.
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MeSH Terms
Apnea / epidemiology
Bacterial Infections / epidemiology*
Bronchiolitis / epidemiology
Critical Illness / epidemiology*
Emergency Service, Hospital / statistics & numerical data
Follow-Up Studies
Infant, Newborn
Meningitis, Viral / epidemiology
Philadelphia / epidemiology
Prospective Studies

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