Document Detail


Serial ultrasonographic observation of bilateral thalami in low birth weight infants with periventricular leukomalacia.
MedLine Citation:
PMID:  20800982     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Periventricular leukomalacia is a major form of neuropathology in preterm infants that is associated with adverse motor and cognitive outcomes. The volume of periventricular white matter and corpus callosum has been reported to be diminished in infants with PVL, and the degree of the volume loss is correlated with the severity of neurological impairment. The thalamic index was calculated from the length, height, width of the thalamus, and thalamic volume was calculated using the formula for an ovoid in 62 low birth weight infants with gestational ages of 24-35weeks, 51 control infants (cerebral palsy, 1 case), and 11 infants diagnosed with PVL (cerebral palsy, 7 cases) at postnatal days0-70. The indices of the right thalamus were lower in infants with PVL than in control infants from day0 to day70, and there were significant differences on days 21, 28, 35, 42, 49, 56, 63, and 70. The indices of the left thalamus were lower in infants with PVL than in control infants from day0 to day70, and there were significant differences on days 21, 28, 35, 42, 49, 56, 63, and 70. The results of the present study suggest that the volume of the thalami is reduced and that thalamic injury is associated with white matter lesions in infants with PVL.
Authors:
Sumio Fukuda; Kyoko Yokoi; Satoshi Suzuki; Haruo Goto
Publication Detail:
Type:  Journal Article     Date:  2010-08-30
Journal Detail:
Title:  Brain & development     Volume:  33     ISSN:  1872-7131     ISO Abbreviation:  Brain Dev.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7909235     Medline TA:  Brain Dev     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  394-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.
Affiliation:
Department of Pediatrics, Johoku Municipal Hospital, Western Medical Center, 2-15 Kaneda, Kita, Nagoya, Aichi 462-0033, Japan.
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