Document Detail

Serial six year quantitative angiographic follow up in asymptomatic patients following successful coronary angioplasty.
MedLine Citation:
PMID:  15367518     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate long term (six years) lumen changes after balloon angioplasty by using quantitative coronary angiography. METHODS: Complete serial quantitative coronary angiography (before and after angioplasty and at six months, three years, and six years) was performed in 100 patients with successful angioplasty and without subsequent repeated revascularisation. In all, 198 dilated segments were compared with 395 non-dilated segments that were obtained from non-target arteries of study patients. RESULTS: From six months to three years after angioplasty, minimum lumen diameter (MLD) increased significantly by 0.13 (0.28) (mean (SD)) mm in dilated segments and decreased significantly by 0.04 (0.27) mm in non-dilated segments. From three years to six years, MLD remained stable in dilated segments but decreased further (by 0.04 (0.28) mm) in non-dilated segments. Consequently, the DeltaMLD between six months and six years was larger in dilated segments than in non-dilated segments (0.12 (0.32) v -0.08 (0.34); p < 0.001). Further, DeltaMLD from six months to six years correlated positively with the percentage diameter stenosis (DS) at six months in each group (dilated segments r = 0.47, p < 0.0001; non-dilated segments r = 0.49, p < 0.0001). Multivariate analysis showed that the only independent predictor of DeltaMLD over six years for each group was the DS at six months. CONCLUSIONS: Lesion regression occurs within the first three years after angioplasty and reaches a plateau thereafter. Moreover, the stenosis severity at six months predicts the magnitude of late regression after angioplasty.
Y Takeda; T Kobayashi; N Awata; S Sato; J H C Reiber; T Nakagawa; E Tsuchikane; O Katoh; M Kirino; T Kobayashi; K Yachiku; N Shibata
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  90     ISSN:  1468-201X     ISO Abbreviation:  Heart     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-09-15     Completed Date:  2004-10-04     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  England    
Other Details:
Languages:  eng     Pagination:  1179-82     Citation Subset:  AIM; IM    
Department of Cardiology, Osaka Medical Centre for Cancer and Cardiovascular Diseases, 1-3-3 Nakamichi, Higashinariku, Osaka City, Osaka 537-8511, Japan.
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MeSH Terms
Analysis of Variance
Angioplasty, Transluminal, Percutaneous Coronary*
Coronary Angiography*
Coronary Disease / radiography,  therapy*
Coronary Restenosis / radiography
Follow-Up Studies
Middle Aged
Prospective Studies
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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