Document Detail

Serial quantitative coronary analyses for the evaluation of one-year change in saphenous vein grafts.
MedLine Citation:
PMID:  18222257     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: A paucity of data exists with respect to changes in whole saphenous vein grafts (SVGs) despite accelerated atherosclerosis within grafted saphenous vein conduits. In the present study, we evaluated the one-year change in SVGs by means of quantitative coronary analysis. METHODS: This study enrolled consecutive 52 patients with 109 SVGs, who underwent coronary artery bypass graft surgery successfully. A follow-up study was performed in 33 patients with 65 SVGs after one year because 16 SVGs were obstructed (baseline, 8; follow-up period, 8), and 15 patients with 28 SVGs dropped out within one year. RESULTS: Both minimal and mean lumen diameters decreased significantly (3.17 +/- 0.64 mm vs 2.41 +/- 0.57 mm, p < 0.001; 3.70 +/- 0.69 mm vs 2.92 +/- 0.70 mm, p < 0.001; respectively). Graft length also decreased significantly (107.1 +/- 25.8 vs 100.6 +/- 25.2 mm, p < 0.001). The graft shortening rate (graft shortening length/baseline graft length x 100) was greater than 5% in 33 vessels (51%) and greater than 10% in 23 vessels (35%). Coronary risk factors (smoking, diabetes mellitus, hypertension, dyslipidemia) did not reveal significant relationship with late loss of minimal and mean lumen diameters. CONCLUSIONS: The present study showed a considerable and uniform lumen loss of SVGs after one year, irrespective of coronary risk factors. Graft length shortening was seen more than elongation.
Nobuaki Suzuki; Ken Kozuma; Yasunari Ueno; Kensuke Nagaoka; Hiroyuki Kyono; Shuichi Ishikawa; Hidenori Watanabe; Naoyuki Yokoyama; Satoshi Takeshita; Takaaki Isshiki
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Publication Detail:
Type:  Journal Article; Retracted Publication    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  85     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-28     Completed Date:  2008-03-11     Revised Date:  2009-02-05    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  525-9     Citation Subset:  AIM; IM    
Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
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MeSH Terms
Cohort Studies
Coronary Angiography / methods
Coronary Artery Bypass / adverse effects,  methods*
Coronary Stenosis / radiography,  surgery*
Evaluation Studies as Topic
Follow-Up Studies
Graft Occlusion, Vascular / epidemiology*,  radiography
Graft Survival
Middle Aged
Monitoring, Physiologic / methods
Risk Assessment
Saphenous Vein / transplantation*
Time Factors
Vascular Patency
Retraction In:
Ann Thorac Surg. 2008 Nov;86(5):1726   [PMID:  19068508 ]

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