Document Detail

Serial pulmonary function in patients with acute heart failure.
MedLine Citation:
PMID:  6830378     Owner:  NLM     Status:  MEDLINE    
This study delineates the effects of congestive heart failure on routine pulmonary function tests and assesses the changes in pulmonary function as congestive heart failure was treated. Twenty-eight patients had spirometry, lung volumes, and diffusing capacity measurements initially and at frequent intervals after their initial hospitalization for congestive heart failure. Initially the patients had both obstructive (mean forced expiratory volume in 1 s [FEV1], 48.2% +/- 13% predicted) and restrictive (mean forced vital capacity [FVC], 5.6% +/- 15.7% predicted) ventilatory dysfunction, but a normal carbon monoxide diffusing capacity. With treatment, pulmonary function rapidly improved initially and there was no further significant improvements in the mean pulmonary function after two weeks of treatment. However, there was marked interindividual variability and several patients took months to reach their best level of pulmonary function. Even with treatment, the patients retained evidence of obstructive ventilatory dysfunction and at the time of their best spirometry 53% (8/15) of nonsmokers still had an abnormally low FEV1/FVC ratio.
R W Light; R B George
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  143     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1983 Mar 
Date Detail:
Created Date:  1983-04-07     Completed Date:  1983-04-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  429-33     Citation Subset:  AIM; IM    
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MeSH Terms
Follow-Up Studies
Heart Failure / physiopathology*
Lung Volume Measurements
Middle Aged
Orciprenaline / pharmacology
Pulmonary Ventilation / drug effects
Time Factors
Reg. No./Substance:

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