| Serial measurements of exercise performance in pediatric heart transplant patients using stress echocardiography. | |
| | |
MedLine Citation:
|
PMID: 21492351 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Yeung JP, Human DG, Sandor GGS, De Souza AM, Potts JE. Serial measurements of exercise performance in pediatric heart transplant patients using stress echocardiography. Pediatr Transplantation 2011: 15: 265-271. © 2011 John Wiley & Sons A/S. Abstract: Heart transplantation is an increasingly acceptable therapeutic option for children with end-stage and complex congenital heart disease. With advances in surgery, immunosuppression, and follow-up care, functional outcomes need to be evaluated. We report the results of serial exercise testing performed using stress echocardiography in a cohort of pediatric HTP. HTP (n = 7) exercised on a semi-recumbent ergometer to volitional fatigue. Echocardiography-Doppler measurements, HR, and blood pressure were taken at rest and during staged exercise. Results were compared with healthy CON (n = 12). HTP did significantly less work during exercise (940 vs. 1218 J/kg, p < 0.03). Their SVI (33 vs. 49 mL/m(2) , p < 0.003), CI (5.16 vs. 9.25 L/min/m(2) , p < 0.0005), and HR (162 vs. 185 bpm, p < 0.02) were lower at peak exercise. HTP had a lower SF at peak exercise (48% vs. 52%, p < 0.03) and an abnormal relationship between the MVCFc and σPS. During follow-up, hemodynamics and left ventricular function remained relatively constant in HTP. HTP are able to exercise safely; however, their exercise tolerance is reduced, and hemodynamics and contractility are diminished. Over time, their hemodynamics and left ventricular function have remained relatively constant. |
| | |
Authors:
|
Joanne P Yeung; Derek G Human; George G S Sandor; Astrid M De Souza; James E Potts |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Pediatric transplantation Volume: 15 ISSN: 1399-3046 ISO Abbreviation: Pediatr Transplant Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-04-15 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9802574 Medline TA: Pediatr Transplant Country: Denmark |
Other Details:
|
Languages: eng Pagination: 265-71 Citation Subset: IM |
Copyright Information:
|
© 2011 John Wiley & Sons A/S. |
Affiliation:
|
Department of Pediatrics Division of Cardiology, Department of Pediatrics, BC Children's Hospital, The University of British Columbia, Vancouver, BC, Canada. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Mycophenolate mofetil in pediatric renal transplantation: A single center experience.
Next Document: Asymptomatic high Epstein-Barr viral load carriage in pediatric renal transplant recipients.