Document Detail

Serial measurement of regional cerebral blood flow in patients with SAH using 133Xe inhalation and emission computerized tomography.
MedLine Citation:
PMID:  6609228     Owner:  NLM     Status:  MEDLINE    
A noninvasive three-dimensional method for measuring cerebral blood flow (CBF), xenon-133 inhalation and emission computerized tomography, was used to investigate the CBF changes accompanying delayed neurological deterioration following subarachnoid hemorrhage (SAH). A total of 67 measurements were performed on 20 patients in Hunt and Hess' clinical Grades I to III in the first 21 days post SAH. Five patients with normal CBF tomograms on admission developed delayed neurological deficits in the 2nd week after hemorrhage, at which time repeat CBF tomograms in four patients revealed large areas of well defined regional flow decrease in the vascular territories of the anterior or middle cerebral arteries. Severe vasospasm was noted in three of these patients in whom arteriography was performed in the 2nd week post SAH. Diffuse bihemispheric CBF decreases were noted later in the course of delayed neurological deficits; however, measurements obtained soon after the onset of focal symptoms suggest that the only CBF decreases directly produced by vasospasm in Grade III patients are regional changes.
B Mickey; S Vorstrup; B Voldby; H Lindewald; A Harmsen; N A Lassen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  60     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  1984 May 
Date Detail:
Created Date:  1984-06-11     Completed Date:  1984-06-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  916-22     Citation Subset:  AIM; IM    
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MeSH Terms
Brain / radionuclide imaging*
Cerebrovascular Circulation*
Middle Aged
Radioisotopes / diagnostic use
Subarachnoid Hemorrhage / radionuclide imaging*
Tomography, Emission-Computed*
Xenon / diagnostic use
Reg. No./Substance:
0/Radioisotopes; 7440-63-3/Xenon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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