Document Detail


Serial hexachlorophene blood levels in the premature infant.
MedLine Citation:
PMID:  1056551     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The concentration of hexachlorophene was determined in serial blood samples taken from seven premature infants washed with pHisoHex. Results indicated that after a single wash with 5ml of pHisoHex, blood concentrations reached a maximum of 0.75-1.20mug/ml two to four days after application. The results obtained in this study confirm that the dermal absorption of hexachlorophene is greater in premature than in full-term infants. Use of hexachlorophene for infants. Use of hexachlorophene for infants of birth weight less than 2kg has now been discontinued at Queen Mary Hospital and the amount of pHisoHex used in the initial toileting of infants with birth weight more than 2kg has been limited to a single application of 5ml.
Authors:
S J Greaves; D G Ferry; E G McQueen; D S Malcolm; P M Buckfield
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The New Zealand medical journal     Volume:  81     ISSN:  0028-8446     ISO Abbreviation:  N. Z. Med. J.     Publication Date:  1975 Apr 
Date Detail:
Created Date:  1975-09-13     Completed Date:  1975-09-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401067     Medline TA:  N Z Med J     Country:  NEW ZEALAND    
Other Details:
Languages:  eng     Pagination:  334-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Birth Weight
Chromatography, Gas
Gestational Age
Hexachlorophene / blood*,  metabolism
Humans
Infant Care
Infant, Newborn
Infant, Premature*
Skin Absorption
Time Factors
Chemical
Reg. No./Substance:
70-30-4/Hexachlorophene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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