Document Detail


Serial echocardiography in transplanted heart: an initial report of five cases.
MedLine Citation:
PMID:  9291650     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Role of echocardiography including Doppler is established in selection of donor and in the care of patients after cardiac transplantation. Its value for recognition of transplant rejection is however still evolving. We present here, serial echocardiographic findings in five male patients, aged 22 to 46 years who underwent cardiac transplantation at our institution. There was no appreciable change on follow-up in the left ventricular dimensions, thickness of left ventricular posterior wall and interventricular septum and left ventricular systolic function. Transient pericardial effusion was noted in two patients. Trivial to mild mitral and tricuspid regurgitation was observed. The diastolic function of the left ventricle, as assessed by mitral valve inflow wave pattern, was normal in four patients. However in the fifth patient, there was evidence of diastolic dysfunction of the left ventricle and this change was accompanied by rejection episode (IIIB changes) in the endomyocardial biopsy. With resolution of rejection in biopsy, the diastolic function by Doppler also returned to normal. We conclude that echocardiography has a definite role in the general care of patients after cardiac transplantation. Transient small pericardial effusion and mild atrioventricular valve regurgitation are common after the operation. Echocardiography may also be of use in recognition of rejection episode by demonstrating evidence of diastolic dysfunction of the left ventricle. Currently, endomyocardial biopsy remains the gold standard for diagnosis of rejection.
Authors:
A Saxena; K K Talwar; S Srivastav; B Airan; D Thatai; P Chopra; P Venugopal
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian heart journal     Volume:  49     ISSN:  0019-4832     ISO Abbreviation:  Indian Heart J     Publication Date:    1997 May-Jun
Date Detail:
Created Date:  1997-09-26     Completed Date:  1997-09-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374675     Medline TA:  Indian Heart J     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  279-82     Citation Subset:  IM    
Affiliation:
Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi.
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MeSH Terms
Descriptor/Qualifier:
Adult
Echocardiography* / methods
Follow-Up Studies
Graft Rejection / ultrasonography*
Heart Transplantation / ultrasonography*
Humans
Male
Middle Aged
Pericardial Effusion / ultrasonography
Postoperative Complications / ultrasonography*
Time Factors
Ventricular Dysfunction, Left / ultrasonography

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