| Serial changes in regional blood flow in the cerebrum and cerebellum of stroke patients imaged by 99Tcm-HMPAO SPET. | |
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MedLine Citation:
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PMID: 8692487 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Luxury perfusion is a well-known phenomenon that can mask ischaemic lesions in patients with cerebral infarction, thus making diagnosis difficult. In this study, we evaluated the incidence of luxury perfusion over a 3-week period following a stroke episode. The usefulness of crossed cerebellar diaschisis (CCD) as a complementary feature in the diagnosis of cerebral infarction was also evaluated using 99Tcm-hexamethylpropyleneamine oxime (99TcmHMPAO) brain single photon emission tomography (SPET). Twelve patients diagnosed as having a hemispheric ischaemic stroke of the middle cerebral arterial territory were enrolled in the study. Each patient underwent a total of four 99Tcm-HMPAO brain SPET examinations, 1 day, 1 week, 2 weeks and 3 weeks following the stroke episode. Our results show that the incidence of luxury perfusion was 67% (8/12) after 1 week, 75% (9/12) after 2 weeks and 83% (10/12) after 3 weeks. The incidence of CCD was 33% (4/12) after 1 day, 50% (6/12) after 1 week, 42% (5/12) after 2 weeks and 33% (4/12) after 3 weeks. We conclude that the detection of cerebral infarction is difficult 2 weeks or more after a stroke episode. The interval between the stroke episode and examination must be considered when reading the 99Tcm-HMPAO image. In addition, CCD may be helpful for the diagnosis of cerebral infarction within the first week after a stroke episode, especially in cases of an unidentified ischaemic region on the 99Tcm-HMPAO hemispheric image. However, the value of CCD is limited 2 weeks or more following the stroke episode. |
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Authors:
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W Y Lin; C H Kao; P Y Wang; S P Changlai; S J Wang |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nuclear medicine communications Volume: 17 ISSN: 0143-3636 ISO Abbreviation: Nucl Med Commun Publication Date: 1996 Mar |
Date Detail:
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Created Date: 1996-08-23 Completed Date: 1996-08-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8201017 Medline TA: Nucl Med Commun Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 208-11 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan, Republic of China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Brain / radionuclide imaging* Cerebellum / blood supply* Cerebral Arteries Cerebrovascular Circulation* Cerebrovascular Disorders / physiopathology, radionuclide imaging* Female Follow-Up Studies Functional Laterality Humans Male Middle Aged Organotechnetium Compounds / diagnostic use* Oximes / diagnostic use* Regional Blood Flow Technetium Tc 99m Exametazime Time Factors Tomography, Emission-Computed* |
| Chemical | |
Reg. No./Substance:
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0/Organotechnetium Compounds; 0/Oximes; 100504-35-6/Technetium Tc 99m Exametazime |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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