Document Detail


Serial autofluorescence imaging over two years following indocyanine green-assisted internal limiting membrane peel for macular hole.
MedLine Citation:
PMID:  16181288     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 65-year-old patient with an idiopathic full-thickness macular hole underwent a vitrectomy, inner limiting membrane (ILM) peel and gas tamponade. The ILM was stained using 0.5% indocyanine green (ICG). Postoperative autofluorescence imaging shows a central focal hyperfluorescence surrounded by a perifoveal hypofluoresecnt area corresponding to the dyed and peeled ILM. Serial autofluorescence images showed progressive decrease in staining until 2 years later when no signs of ICG autofluorescence were apparent. The visual acuity for this patient improved two Snellen lines from 6/36 to 6/18 at 2 years. ICG may not be clinically toxic as is currently feared.
Authors:
Thomas L Kersey; Anne Bolton; C K Patel
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Publication Detail:
Type:  Case Reports; Letter    
Journal Detail:
Title:  Clinical & experimental ophthalmology     Volume:  33     ISSN:  1442-6404     ISO Abbreviation:  Clin. Experiment. Ophthalmol.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-26     Completed Date:  2006-01-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100896531     Medline TA:  Clin Experiment Ophthalmol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  538-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Basement Membrane / pathology,  surgery
Coloring Agents / diagnostic use
Diagnostic Imaging
Female
Fluorescence
Follow-Up Studies
Humans
Indocyanine Green / diagnostic use*
Prone Position
Retinal Perforations / diagnosis*,  surgery
Sulfur Hexafluoride / administration & dosage
Tomography, Optical Coherence
Vitrectomy
Chemical
Reg. No./Substance:
0/Coloring Agents; 2551-62-4/Sulfur Hexafluoride; 3599-32-4/Indocyanine Green

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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