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Sequential use of bare-metal stents and drug-coated balloons to treat coronary artery stenosis.
MedLine Citation:
PMID:  23117308     Owner:  NLM     Status:  In-Data-Review    
INTRODUCTION: Drug-coated balloons (DCBs) are increasingly used in percutaneous coronary intervention (PCI). The sequential use of DCB and bare-metal stent (BMS) represents a novel approach and results of pilot studies have been encouraging. The aim of this study was to assess long-term outcomes of patients who received treatment with DCB and BMS and additionally study whether the order (BMS or DCB first) affected outcomes.
METHODS: This is a single-center, non-randomized, prospective study of patients who underwent PCI between July 2009 and July 2011. Two groups were defined: DCB followed by BMS (DCB→BMS) or BMS followed by DCB (BMS→DCB). Our primary outcome was target lesion revascularization (TLR) at 7 months.
RESULTS: A total of 128 patients (173 lesions) with a mean age of 67 years were included. The BMS→DCB group consisted of 53 patients (78 lesions) and the DCB→BMS group consisted of 75 patients (95 lesions). The mean follow-up was 7.4 months. The TLR rate was 4/76 (5%) in the BMS→DCB group and 3/90 (3%) in the DCB→BMS group (P=.83).
CONCLUSION: Our study demonstrates good results of sequential BMS and DCB use in an all-comers population. If confirmed by larger studies, this could be a valuable approach in patients with contraindications to drug-eluting stent implantation.
Remo Beeler; Florim Cuculi; Mabelle Young; Paul Erne
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  24     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  555-9     Citation Subset:  IM    
Department of Cardiology, Luzerner Kantonsspital, 6000 Luzern 16, Switzerland.
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