Document Detail

Sequence analysis of two de novo mutation alleles at the DXS10011 locus.
MedLine Citation:
PMID:  14568776     Owner:  NLM     Status:  MEDLINE    
We have detected two unusual alleles at the DXS10011 locus in two paternity trio cases. In one case, one allele of the daughter was found not to have been derived from the mother but the other allele was shared with the father. In the other case, the mother and the son shared no bands. Paternity in both cases was established using conventional polymorphic markers in addition to DNA markers (probabilities: >0.999999). Sequencing showed that the two de novo alleles of the children acquired a single unit (GAAA).
Akiyoshi Tamura; Misa Iwata; Izumi Takase; Tokiko Miyazaki; Kiyoshi Matsui; Hajime Nishio; Koichi Suzuki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Legal medicine (Tokyo, Japan)     Volume:  5     ISSN:  1344-6223     ISO Abbreviation:  Leg Med (Tokyo)     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-10-21     Completed Date:  2004-05-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100889186     Medline TA:  Leg Med (Tokyo)     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  161-4     Citation Subset:  IM    
Department of Legal Medicine, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka 569-8686, Japan.
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MeSH Terms
Chromosomes, Human, X
Genetic Markers
Sequence Analysis, DNA
Tandem Repeat Sequences
Reg. No./Substance:
0/Genetic Markers

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