Document Detail


Sequence analysis of the VP7 gene of human rotavirus G1 isolated in Japan, China, Thailand, and Vietnam in the context of changing distribution of rotavirus G-types.
MedLine Citation:
PMID:  17516525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Over the last decade, rotavirus G1 has represented the most common genotype worldwide. Since 2000, the prevalence of rotavirus G1 has decreased in some countries such as Japan and China. To monitor the trend of the VP7 encoding gene of rotavirus G1, we performed a sequence analysis of 74 G1 rotavirus strains isolated in Japan, China, Thailand, and Vietnam during the period from 2002 to 2005. The phylogenetic tree showed that all of the studied G1 strains from the four countries clustered into lineage III, the same as the majority of the G1 strains isolated in China and Japan in 1990 and 1991. Examination of the deduced amino acid sequences of the G1 strains from China and Japan revealed an amino acid substitution at position 91 (Asn instead of Thr) in antigenic region A when compared to the G1 strains isolated in China and Japan in 1990, 1991, and global reference strains. For the G1 strains from Thailand and Vietnam, there were three amino acid substitutions, not belonging to any antigenic regions. The study showed that there have been no considerable changes of human rotavirus G1 isolated in Japan, China, Thailand, and Vietnam. Further studies need to be carried out for a better understanding of why such changes in the prevalence of rotavirus G1 occur in these countries.
Authors:
Quang Duy Trinh; Tuan Anh Nguyen; Tung Gia Phan; Pattara Khamrin; Hainian Yan; Phuc Le Hoang; Niwat Maneekarn; Yan Li; Fumihiro Yagyu; Shoko Okitsu; Hiroshi Ushijima
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of medical virology     Volume:  79     ISSN:  0146-6615     ISO Abbreviation:  J. Med. Virol.     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-05-28     Completed Date:  2007-08-07     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7705876     Medline TA:  J Med Virol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1009-16     Citation Subset:  IM    
Affiliation:
Department of Developmental Medical Sciences, Institute of International Health, Graduate School of Medicine, University of Tokyo, Japan.
Data Bank Information
Bank Name/Acc. No.:
GENBANK/DQ508167;  DQ512968;  DQ512969;  DQ512970;  DQ512971;  DQ512972;  DQ512973;  DQ512974;  DQ512975;  DQ512976;  DQ512977;  DQ512978;  DQ512979;  DQ512980;  DQ512981;  DQ512982;  DQ512983;  DQ512984;  DQ512985;  DQ512986;  DQ512987;  DQ512988;  DQ512989;  DQ512990;  DQ512991;  DQ512992;  DQ512993;  DQ512994;  DQ512995;  DQ512996;  DQ512997;  DQ512998;  EF088833;  EF088834;  EF088835;  EF088836;  EF088837;  EF088838
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MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Amino Acid Substitution
Antigens, Viral / genetics*,  immunology
Base Sequence
Capsid Proteins / genetics*,  immunology
Child, Preschool
China / epidemiology
DNA Primers / genetics
DNA, Viral / genetics
Genes, Viral
Humans
Infant
Japan / epidemiology
Molecular Epidemiology
Molecular Sequence Data
Phylogeny
Rotavirus / classification,  genetics*,  immunology,  isolation & purification*
Rotavirus Infections / epidemiology*,  virology*
Sequence Homology, Amino Acid
Thailand / epidemiology
Time Factors
Vietnam / epidemiology
Chemical
Reg. No./Substance:
0/Antigens, Viral; 0/Capsid Proteins; 0/DNA Primers; 0/DNA, Viral; 0/VP7 protein, Rotavirus

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