Document Detail

Sequelae of caffeine treatment in preterm infants with apnea.
MedLine Citation:
PMID:  363996     Owner:  NLM     Status:  MEDLINE    
Growth, neurologic, and ophthalmologic assessments were done in 21 low-birth-weight infants given caffeine for neonatal apnea and in 21 matched control infants. Caffeine significantly decreased the need for and the duration of mechanical ventilation. No difference in growth and development was noted between the control and caffeine-treated infants. A high incidence of cicatricial retrolental fibroplasia was observed in both control (10/21) and caffeine-treated infants (7/18).
T R Gunn; K Metrakos; P Riley; D Willis; J V Aranda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  94     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1979 Jan 
Date Detail:
Created Date:  1979-02-21     Completed Date:  1979-02-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  106-9     Citation Subset:  AIM; IM    
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MeSH Terms
Apnea / complications,  drug therapy*
Caffeine / adverse effects,  therapeutic use*
Child Development / drug effects*
Follow-Up Studies
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature, Diseases / drug therapy*
Intermittent Positive-Pressure Ventilation / adverse effects
Nervous System Diseases / complications
Retinopathy of Prematurity / etiology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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