Document Detail


Septic shock in digestive surgery: a retrospective study of 89 patients.
MedLine Citation:
PMID:  20214204     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND/AIMS: septic shock is the most severe systemic inflammatory response to infection. Septic shock is associated with organ dysfunction and with major circulatory failure. The aim of this work is to study the impact of septic shock in digestive surgery. This is a retrospective study. METHODOLOGY: Between January 2001 and March 2008, we selected patients hospitalized in the intensive care unit who underwent digestive surgery and who developed septic shock during the same hospitalization were selected: 89 patients were enrolled in this group which included 53 men and 36 women (sex ratio M/W 1.47), and the age average was 71.5 years. They were divided into two subgroups: preoperative septic shock (62/89) and postoperative (27/89). The majority of septic shock occurred in patients who developed an inflammatory disease and an organ perforation. Esophagogastric surgery generates the most postoperative septic shock. RESULTS: The overall mortality was 54%. The most frequent complications were digestive and pulmonary. The germ most frequently encountered is Escherichia coli. The majority of patients received a combination of two or three antibiotics. The empirical antibiotic therapy most frequently administered was a combination of piperacillin/ tazobactam and amikacin. DISCUSSION: The results observed in the present study are, for the most part, in agreement with those found in the literature. However, the question of the most effective antibiotic therapy remains open. CONCLUSION: In digestive surgery, septic shock is pathology with significant mortality (54%). The germ most frequently responsible is Escherichia coli. The most frequently administered empirical antibiotic therapy is a combination of amikacin and piperacillin.
Authors:
Pascale Hizette; Christian Simoens; Jacques Massaut; Viviane Thill; Dirk Smets; Pierre Mendes da Costa
Related Documents :
7282894 - Treatment of malignant external otitis in its initial stage.
6376404 - Randomized clinical trial of short-term antibiotic prophylaxis in 750 patients undergoi...
19821794 - Antibiotic or bacterial therapy in post-giardiasis irritable bowel syndrome.
20140354 - Nosocomial infections in brazilian pediatric patients: using a decision tree to identif...
18340484 - Endovascular aortic aneurysm repair with the talent stent-graft: outcomes in patients w...
22291934 - Downgrading meld improves the outcomes after liver transplantation in patients with acu...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  56     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2010-03-10     Completed Date:  2010-03-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  1615-21     Citation Subset:  IM    
Affiliation:
Department of Digestive, Thoracic and Laparoscopic Surgery, CHU Brugmann, ULB, Brussels, Belgium.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents / therapeutic use
Digestive System Surgical Procedures / adverse effects*
Female
Humans
Male
Middle Aged
Postoperative Complications / etiology*
Retrospective Studies
Shock, Septic / drug therapy,  etiology*,  microbiology
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Combined nutritional support in patients with chronic obstructive pulmonary disease (COPD), under me...
Next Document:  Therapeutic influence of 20 % albumin versus 6% hydroxyethylstarch on extravascular lung water in se...