Document Detail

Septic arthritis due to Cryptococcus neoformans.
MedLine Citation:
PMID:  3053912     Owner:  NLM     Status:  MEDLINE    
Cryptococcal arthritis is rare. We report two cases, one of infection of the hip joint in a 56-year-old woman, the other of arthritis of the elbows and knees in a 4-year-old boy. Both patients were treated successfully with a combination of surgical drainage and antifungal therapy. The 15 previously published cases are reviewed. Immunodeficiency is noted in most reported cases commonly associated with the use of corticosteroids. The joint most often involved is the knee. Amphotericin B and 5-fluorocytosine have been used with success for treating this conditions. Ketoconoazole may have a role in the therapy of cryptococcal arthritis although information on the use of this agent is sparse.
K J Stead; K P Klugman; M L Painter; H J Koornhof
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Journal of infection     Volume:  17     ISSN:  0163-4453     ISO Abbreviation:  J. Infect.     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1988-12-22     Completed Date:  1988-12-22     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7908424     Medline TA:  J Infect     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  139-45     Citation Subset:  IM    
School of Pathology, University of the Witwatersrand, Johannesburg, South Africa.
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MeSH Terms
Arthritis, Infectious / microbiology*
Child, Preschool
Cryptococcosis / microbiology*
Cryptococcus / isolation & purification*
Cryptococcus neoformans / isolation & purification*
Middle Aged

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