| Septal myotomy-myomectomy versus mitral valve replacement in hypertrophic cardiomyopathy. Ten-year follow-up in 185 patients. | |
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MedLine Citation:
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PMID: 2766539 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Between 1963 and 1985, 185 patients with hypertrophic cardiomyopathy (HCM) were treated with septal myotomy-myomectomy (MM) or mitral valve replacement (MVR) at our institution; 127 of these underwent septal MM, and 58 underwent MVR alone. The 1-month mortality was 4.7% for the septal MM group and 6.9% for the MVR group (p = NS). The mean time of postoperative follow-up was 118 months, ranging between 1 and 196 months. The annual mortality was 0.7% for the septal MM group and 1.3% for the MVR group (p = NS). In the MVR group, 98% of patients had been assigned to New York Heart Association (NYHA) functional classes III and IV before surgery; only 24% were classified as such at 10-year follow-up (p less than 0.001). In the septal MM group, 90% were in NYHA functional classes III and IV before surgery whereas only 27% were in these two classes postoperatively (p less than 0.001). A comparison of preoperative and postoperative hemodynamic findings revealed a significant reduction in left ventricular outflow gradient at rest: from 69 +/- 41 mm Hg preoperatively to 10 +/- 22 mm Hg postoperatively (p less than 0.001) in the septal MM group and from 75 +/- 45 mm Hg preoperatively to 10 +/- 21 mm Hg postoperatively (p less than 0.001) in the MVR group. In addition, the MVR group had a significant postoperative reduction in mean left ventricular end-diastolic pressure, from 21 mm Hg preoperatively to 15 mm Hg postoperatively (p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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Z Krajcer; R D Leachman; D A Cooley; R Coronado |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Circulation Volume: 80 ISSN: 0009-7322 ISO Abbreviation: Circulation Publication Date: 1989 Sep |
Date Detail:
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Created Date: 1989-10-11 Completed Date: 1989-10-11 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0147763 Medline TA: Circulation Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: I57-64 Citation Subset: AIM; IM |
Affiliation:
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Division of Cardiology, Texas Heart Institute, Houston. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Cardiomyopathy, Hypertrophic / complications, mortality, physiopathology, surgery* Child Child, Preschool Female Follow-Up Studies Heart Catheterization Heart Failure / epidemiology Heart Septum / surgery* Heart Valve Prosthesis* Heart Ventricles / physiopathology Humans Male Middle Aged Mitral Valve Postoperative Complications / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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