Document Detail

Sepsis in premature newborns with congenital heart disease.
MedLine Citation:
PMID:  21087428     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the incidence and distribution of neonatal sepsis in premature newborns with congenital heart disease (CHD) according to gestational and postnatal age, time of onset, and type and frequency of causing agents, and compare it with premature newborns without CHD.
DESIGN, SETTING, PATIENTS: A clinical investigation on 80 premature newborns admitted to neonatal intensive care unit (NICU) of Pediatric Clinic University Medical Center Sarajevo, Bosnia and Herzegovina, between October 23, 2007 and March 18, 2009. We analyzed the incidence and distribution of neonatal sepsis in premature newborns with CHD according to gestational and postnatal age, time of onset, and type and frequency of causing agents, and compared it with premature NICU patients without CHD.
RESULTS: Of the 80 premature newborns included in our study, 14 had CHD with patent ductus arteriosus as the most common type of anomaly. Culture-proven sepsis was diagnosed in 28.57% premature newborns with CHD and 12.12% premature newborns without CHD. The three most common causing agents were Staphylococcus aureus, Klebsiella species, and Serratia species.
CONCLUSION: Premature newborns with CHD have a higher risk of acquiring sepsis during hospitalization in NICU, probably because of longer duration of hospitalization and need for invasive procedures such as mechanical ventilation, central venous catheters, and parenteral nutrition.
Emina Hadzimuratovic; Senka Mesihovic Dinarevic; Admir Hadzimuratovic
Related Documents :
8866918 - Theophylline population pharmacokinetics from routine monitoring data in very premature...
476208 - Assessment of ventilation-perfusion inequality by aadn2 in newborn infants.
16547078 - Effect of light reduction on the incidence of retinopathy of prematurity.
8913908 - Manifest and concealed av nodal reentry in wenckebach type of av conduction with av jun...
3393328 - A national study of sudden infant death syndrome in new zealand.
3394728 - Association of maternal hematocrit with premature labor.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Congenital heart disease     Volume:  5     ISSN:  1747-0803     ISO Abbreviation:  Congenit Heart Dis     Publication Date:    2010 Sep-Oct
Date Detail:
Created Date:  2010-11-22     Completed Date:  2011-03-04     Revised Date:  2011-05-05    
Medline Journal Info:
Nlm Unique ID:  101256510     Medline TA:  Congenit Heart Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  435-8     Citation Subset:  IM    
Pediatric Clinic, University Medical Center Sarajevo, Sarajevo, Bosnia and Herzegovina.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Academic Medical Centers
Bosnia-Herzegovina / epidemiology
Case-Control Studies
Cross Infection / epidemiology*,  microbiology
Gestational Age
Heart Defects, Congenital / epidemiology*
Infant, Newborn
Infant, Premature*
Intensive Care Units, Neonatal
Klebsiella / isolation & purification
Retrospective Studies
Risk Assessment
Risk Factors
Sepsis / epidemiology*,  microbiology
Serratia / isolation & purification
Staphylococcus aureus / isolation & purification
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Arrhythmia recurrence in adult patients with single ventricle physiology following surgical Fontan c...
Next Document:  Device closure of patent ductus arteriosus in Marfan patients: safety and effect on the aortic root ...