| Sepsis in burned patients. | |
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MedLine Citation:
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PMID: 15049101 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A prospective study was conducted from June 2001 to May 2002 at the Burns Unit of Hospital Regional da Asa Norte, Brasília, Brazil. During the period of the study, 252 patients were treated at the Burns Unit, 49 (19.4%) developed clinically and microbiologically proven sepsis. Twenty-six (53.1%) were males and 23 (46.9%) females with a mean age of 22 years (range one to 89 years) and mean burned body surface area of 37.7 +/- 18.4% (range 7 to 84%). Forty-three patients had flame burns, five a scald and one an electric burn. These 49 patients had a total of 62 septic episodes. Forty (81.6%) patients had only one and nine (18.4%) had up to three episodes of sepsis. Thirty (61.2%) patients had their first septicemic episode either earlier or by one week postburn. Out of 62 septic episodes, 58 were due to bacteria and four due to Candida sp. The most common bacteria isolated from blood culture were Staphylococccus aureus, coagulase-negative Staphylococcus, Acinetobacter baumannii, Enterobacter cloacae and Klebsiella pneumoniae. Eleven (18.9%) episodes were due to oxacillin resistant Staphylococcus aureus. Acinetobacter baumannii was sensitive to ampicillin/sulbactam in 71.4% and to imipenem in 85.7% of the cases. The primary foci of sepsis were the burn wound in 15 (24.2%) episodes. The most common clinical findings of sepsis in these patients were fever, dyspnea, hypotension and oliguria. The most common laboratory findings of these patients were anemia, leukocytosis, hypoalbuminemia and thrombocytopenia. Twelve (24.5%) patients died. The appropriate knowledge of clinical, epidemiological, laboratorial and microbiological aspects of sepsis in burned patients permits an adequate diagnosis and treatment of this complication. |
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Authors:
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Jefferson Lessa de Macedo; Simone C Rosa; Cleudson Castro |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Revista da Sociedade Brasileira de Medicina Tropical Volume: 36 ISSN: 0037-8682 ISO Abbreviation: Rev. Soc. Bras. Med. Trop. Publication Date: 2003 Nov-Dec |
Date Detail:
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Created Date: 2004-03-30 Completed Date: 2004-05-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7507456 Medline TA: Rev Soc Bras Med Trop Country: Brazil |
Other Details:
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Languages: eng Pagination: 647-52 Citation Subset: IM |
Affiliation:
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Hospital Regional da Asa Norte, Secretaria de Saúde do Distrito Federal, Brasília, DF. 2. Núcleo de Medicina Tropical da Universidade de Brasília, DF. glsmacedo@yahoo.com.br |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Burns / complications*, microbiology Child Child, Preschool Cross Infection / microbiology* Drug Resistance, Bacterial Female Gram-Negative Bacteria / drug effects Gram-Positive Bacteria / drug effects Humans Infant Male Middle Aged Prospective Studies Sepsis / microbiology* Severity of Illness Index |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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