Document Detail

Sepsis bundles and compliance with clinical guidelines.
MedLine Citation:
PMID:  21670090     Owner:  NLM     Status:  In-Data-Review    
Realizing the vast medical benefits of validated protocols, recommendations and practice guidelines requires acceptance and implementation by frontline care providers. Knowledge translation is the science of accelerating the transfer of knowledge to practice by understanding and creatively addressing the barriers that prevent adoption of new professional standards. In an attempt to improve patient care and reduce mortality, the Surviving Sepsis Campaign and The Institute for Healthcare Improvement created the resuscitation and management bundles for patients with severe sepsis and septic shock. These bundles have been accepted as best practice by many clinicians since multiple clinical trials have produced similar positive results when they were implemented. However, transferring these research outcomes-based guidelines to the clinical practice arena has been associated with poor compliance due to important barriers to implementation. Delays in the adoption of sepsis bundles are not surprising since the time from validation to implementation of a new clinical practice is typically 17 years. Using sepsis bundles as a model, this article explores why guidelines are important, examines physician adherence to protocols, and reviews the literature on strategies to improve clinical compliance and enhance knowledge translation.
Lisa Stoneking; Kurt Denninghoff; Lawrence Deluca; Samuel M Keim; Benson Munger
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of intensive care medicine     Volume:  26     ISSN:  1525-1489     ISO Abbreviation:  J Intensive Care Med     Publication Date:    2011 May-Jun
Date Detail:
Created Date:  2011-06-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610344     Medline TA:  J Intensive Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  172-82     Citation Subset:  IM    
Department of Emergency Medicine, The University of Arizona College of Medicine, Tucson, AZ, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Expression and function of toll-like receptors in peripheral blood mononuclear cells of patients wit...
Next Document:  Age-related medical decision limits for urinary free (unconjugated) metadrenalines, catecholamines a...