| Sepsis biomarkers in polytrauma patients. | |
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MedLine Citation:
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PMID: 21440205 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Despite continual advances in medical care and injury prevention efforts, traumatic injury remains a leading cause of death of Americans with these deaths occurring in a tri-modal pattern. The early phases of this pattern are characterized by immune activation whereas the last phase is marked by profound immune dysfunction. It is during this last phase that many trauma patients die of septic complications pointing to a dire need for a specific biomarker for post-traumatic infection. This article discusses several biomarkers, including emerging ones, for infection and sepsis following trauma including inflammatory cytokines, intracellular proteins, and cellular biomarkers. |
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Authors:
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Charles A Adams |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Critical care clinics Volume: 27 ISSN: 1557-8232 ISO Abbreviation: Crit Care Clin Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8507720 Medline TA: Crit Care Clin Country: United States |
Other Details:
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Languages: eng Pagination: 345-54 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Warren Alpert School of Medicine of Brown University, Providence, RI, USA; Division of Trauma and Surgical Critical Care, Rhode Island Hospital, 593 Eddy Street, APC 453, Providence, RI 02903, USA; Surgical and Trauma Intensive Care Units, Rhode Island Hospital, Providence, RI 02903, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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