Document Detail


Sepsis and adrenal function.
MedLine Citation:
PMID:  18407225     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
In the setting of sepsis, adrenal function can be difficult to evaluate. Cortisol levels, normally elevated by the stress of sepsis, are occasionally reduced, signifying possible adrenal dysfunction. Even elevated cortisol levels do not assure that adrenal reserve is adequate and may in fact portend a preterminal state. Bilateral adrenal hemorrhage leading to adrenal insufficiency is one complication of the sepsis syndrome. This endocrine rounds illustrates the importance in considering adrenal insufficiency and adrenal hemorrhage in patients with overwhelming sepsis while discussing the pathophysiology, clinical presentation, and therapeutic implications of this dire complication.
Authors:
L M Siegel; S K Grinspoon; G J Garvey; J P Bilezikian
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Publication Detail:
Type:  Clinical Conference; Journal Article    
Journal Detail:
Title:  Trends in endocrinology and metabolism: TEM     Volume:  5     ISSN:  1043-2760     ISO Abbreviation:  Trends Endocrinol. Metab.     Publication Date:  1994 Oct 
Date Detail:
Created Date:  2008-04-14     Completed Date:  2009-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001516     Medline TA:  Trends Endocrinol Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  324-8     Citation Subset:  -    
Affiliation:
Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
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