Document Detail


Separation of mismatch negativity and the N1 wave in the auditory cortex of the cat: a topographic study.
MedLine Citation:
PMID:  11336892     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The amplitude distribution of the frequency mismatch negativity (MMN) and that of P1 and N1 components were investigated in cats to reveal their sources in the auditory areas of the neocortex. METHODS: Pure tone stimuli were given in a passive oddball paradigm with different degrees of deviance between the standard and deviant tones. Amplitude maps of event-related potential (ERP) components were generated from the responses, recorded in awake, freely moving animals by a chronically implanted epidural electrode matrix, covering both the primary and secondary auditory fields. RESULTS: The P1 and N1 components appeared with highest amplitude on the middle ectosylvian gyrus, while the amplitude maximum of the MMN was ventral and rostral to them on the AII area. Both the latency and the peak amplitude of the MMN depended on the degree of deviance. CONCLUSIONS: The MMN is generated in the rostroventral part of the secondary auditory area, well separated from the sources of the P1 and N1 components.
Authors:
Z Pincze; P Lakatos; C Rajkai; I Ulbert; G Karmos
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology     Volume:  112     ISSN:  1388-2457     ISO Abbreviation:  Clin Neurophysiol     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-05-04     Completed Date:  2001-06-28     Revised Date:  2008-09-10    
Medline Journal Info:
Nlm Unique ID:  100883319     Medline TA:  Clin Neurophysiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  778-84     Citation Subset:  IM    
Affiliation:
Institute for Psychology of the Hungarian Academy of Sciences, Budapest, Hungary. pincze@cogpsyphy.hu
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation
Analysis of Variance
Animals
Audiometry, Pure-Tone
Auditory Cortex / physiology*
Auditory Pathways / physiology*
Brain Mapping*
Cats
Electrophysiology / methods
Evoked Potentials / physiology*
Reaction Time

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