Document Detail

Separation of major catechins from green tea by ultrahigh pressure extraction.
MedLine Citation:
PMID:  19874878     Owner:  NLM     Status:  MEDLINE    
This study presents a novel extraction technique, ultrahigh pressure extraction, to obtain major catechins from green tea leaves. The effects of various high pressure level (100, 200, 300, 400, 500, 600 MPa) on the extract are examined. HPLC chromatographic analyses determine the concentration of four major catechins and caffeine. The extraction yields of active ingredients with ultrahigh pressure extraction (400 MPa pressure) for only 15 min were given the same as those of organic solvent extraction for 2h. These excellent results for the ultrahigh pressure extraction are promising for the future separation of active ingredients from traditional Chinese herbal medicine.
Xi Jun; Zhao Shuo; Lu Bingbing; Zhang Rui; Li Ye; Shen Deji; Zhou Guofeng
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Publication Detail:
Type:  Journal Article     Date:  2009-10-27
Journal Detail:
Title:  International journal of pharmaceutics     Volume:  386     ISSN:  1873-3476     ISO Abbreviation:  Int J Pharm     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-01     Completed Date:  2010-04-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7804127     Medline TA:  Int J Pharm     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  229-31     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier B.V. All rights reserved.
School of Chemical Engineering, Sichuan University, Chengdu 610065, China.
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MeSH Terms
Caffeine / isolation & purification
Camellia sinensis / chemistry*
Catechin / analogs & derivatives,  isolation & purification*
Chemical Fractionation / methods*
Chromatography, High Pressure Liquid
Plant Leaves
Solvents / chemistry
Time Factors
Reg. No./Substance:
0/Solvents; 154-23-4/Catechin; 1617-55-6/gallocatechol; 58-08-2/Caffeine; 863-03-6/epicatechin gallate; 989-51-5/epigallocatechin gallate

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