| Separating arterial and venous components from 3D dynamic contrast-enhanced MRI studies using factor analysis. | |
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MedLine Citation:
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PMID: 12704776 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Dynamic contrast-enhanced MRI has been used extensively for angiography but in order to generate separate arterial and venous images some form of postprocessing is required. This typically involves the subtraction of one image in a dynamic sequence from another in order to suppress unwanted signal; however, this also has the effect of decreasing the signal-to-noise ratio (SNR) of the image. In this study, factor analysis, a technique related to eigenimage filtering, is used to separate arterial and venous components from dynamic contrast-enhanced images of the legs acquired with a temporal resolution of 30 sec. The SNR of the venous and arterial images extracted from a series of 20 patients using conventional single subtraction, a double subtraction method, and factor analysis were compared. Results show that the use of factor analysis improved the SNR in the venous images by a factor of 2.3 compared with the use of simple subtraction. A subjective comparison of the maximum intensity projection images generated from the venous images was also carried out and showed a significant preference for those generated using factor analysis over those generated using other subtraction methods. |
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Authors:
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Anne L Martel; Doug Fraser; G Steve Delay; Paul S Morgan; Alan R Moody |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: 49 ISSN: 0740-3194 ISO Abbreviation: Magn Reson Med Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-04-21 Completed Date: 2003-09-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: United States |
Other Details:
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Languages: eng Pagination: 928-33 Citation Subset: IM |
Copyright Information:
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Copyright 2003 Wiley-Liss, Inc. |
Affiliation:
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Dept Medical Physics, Queen's Medical Centre, Nottingham, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Contrast Media Factor Analysis, Statistical Humans Image Processing, Computer-Assisted / statistics & numerical data* Magnetic Resonance Angiography / methods*, statistics & numerical data* Phlebography Signal Processing, Computer-Assisted* Statistics, Nonparametric Subtraction Technique Thrombophlebitis / diagnosis*, radiography |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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