Document Detail

Sentinel lymph node biopsy for the staging of anal melanoma: report of two cases.
MedLine Citation:
PMID:  17294674     Owner:  NLM     Status:  MEDLINE    
Primary melanoma of the anal region is a rare pathological entity and its prognosis is generally poor. The aim of this report is to demonstrate the feasibility of the sentinel lymph node (SLN) procedure with combined technique in patients with anal melanoma. We report of two cases with anal melanoma that had wide local excision of the primary lesion and was referred for further evaluation. After diagnostic metastatic work-up, SLN procedure consisted of a combination of preoperative lymphoscintigraphy with technetium-99m nanocolloid injected around the tumor, and intraoperative detection of SLN with gamma probe (combined technique) was performed. In addition, patent blue dye was injected at the periphery of the tumor to facilitate direct identification of the blue-stained lymph node. In the first case, SLN identified both inguinal and iliac lymph node basins, both of which were histologically negative on both frozen and paraffin sections. In the other case, SLN removed from the inguinal lymph node basin showed micrometastasis by paraffin section. In both cases SLN procedure with combined technique was performed sufficiently without significant complications. Consequently, we suggest that SLN procedure with combined technique is also a useful technique in malignant melanomas similar to other anal canal cancers.
Yasemin Sanli; Cuneyt Turkmen; Sidika Kurul; Faruk Taş; Ayşe Mudun; Sema Cantez
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of nuclear medicine     Volume:  20     ISSN:  0914-7187     ISO Abbreviation:  Ann Nucl Med     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2007-02-13     Completed Date:  2007-03-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8913398     Medline TA:  Ann Nucl Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  629-31     Citation Subset:  IM    
Department of Nuclear Medicine, Istanbul University, Faculty of Medicine, Istanbul, Turkey.
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MeSH Terms
Anus Neoplasms / diagnosis*,  pathology
Lymph Nodes / pathology*
Lymphatic Metastasis / diagnosis
Melanoma / diagnosis*,  pathology
Middle Aged
Neoplasm Staging / methods*
Radionuclide Imaging / methods
Sentinel Lymph Node Biopsy / methods*
Technetium Tc 99m Sulfur Colloid / pharmacology
Reg. No./Substance:
0/Technetium Tc 99m Sulfur Colloid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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