| Sensitization to Blomia tropicalis and Lepidoglyphus destructor in Dermatophagoides spp-allergic individuals. | |
| | |
MedLine Citation:
|
PMID: 1744365 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Serum was collected from 77 atopic subjects from Cartagena, Colombia, who had a positive skin test (greater than or equal to 3 mm) to either Dermatophagoides farinae (Df) (73) or D. pteronyssinus (Dp) (70). Twenty-nine healthy volunteers with negative allergy histories and negative skin tests were used as control subjects. RAST and RAST-inhibition assays were used to study the prevalence of specific IgE to Blomia tropicalis (Bt), Lepidoglyphus destructor (Ld), and Df. RAST results were considered positive when a serum bound greater than or equal to 1% of the total counts added; 69 atopic subjects (89.6%) were positive to Df, 66 (85.5%) to Bt, and 46 subjects (59.7%) were positive to Ld. RAST results, analyzed by regression analysis, revealed the following correlation coefficients: Df versus Bt, r = 0.59; Df versus Ld, r = 0.44; and Bt versus Ld, r = 0.52. RAST-inhibition assays with a serum pool of 11 individuals highly allergic to all three mites (mean specific IgE to all mites, greater than or equal to 18.2 percent total counts bound) demonstrated considerable cross-reactivity between Bt and Ld and moderate cross-reactivity between Df and Bt and Ld. Bt, Df, and Ld possess unique, as well as common, allergens. Sensitization to Bt and Ld is very common in mite-allergic individuals in Cartagena, Colombia. |
| | |
Authors:
|
L Puerta Llerena; E Fernández-Caldas; L R Caraballo Gracia; R F Lockey |
Related Documents
:
|
15137895 - Immunocap specific ige test: an objective tool for research and routine allergy diagnosis. 9722225 - Specific ige antibodies in the diagnosis of atopic disease. clinical evaluation of a ne... 7819435 - Multi-centre comparison of abbott matrix aero to pharmacia standard rast, modified rast... 10887305 - Genetics of peanut allergy: a twin study. 7408555 - Susceptibility testing to trimethoprim alone and combined with sulphonamides. 23262145 - Canine brainstem auditory evoked responses are not clinically impacted by head size or ... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
|
Title: The Journal of allergy and clinical immunology Volume: 88 ISSN: 0091-6749 ISO Abbreviation: J. Allergy Clin. Immunol. Publication Date: 1991 Dec |
Date Detail:
|
Created Date: 1992-01-16 Completed Date: 1992-01-16 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 1275002 Medline TA: J Allergy Clin Immunol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 943-50 Citation Subset: AIM; IM |
Affiliation:
|
Laboratory of Immunology, University of Cartagena, Colombia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Allergens / immunology*, isolation & purification Animals Antibody Specificity Cross Reactions / immunology Female Humans Hypersensitivity / immunology* Immunization* Immunoglobulin E / blood Male Mites / immunology* Radioallergosorbent Test Species Specificity |
| Chemical | |
Reg. No./Substance:
|
0/Allergens; 37341-29-0/Immunoglobulin E |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated w...
Next Document: Characterization of allergen-induced bronchial hyperresponsiveness and airway inflammation in active...