Document Detail

Sensitivity to non-acetylated salicylates in a patient with asthma, nasal polyps, and rheumatoid arthritis.
MedLine Citation:
PMID:  3740556     Owner:  NLM     Status:  MEDLINE    
A woman experienced exacerbations of bronchial asthma after taking aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) for rheumatoid arthritis. On oral challenges, she developed an urticarial reaction after tartrazine; urticarial and bronchospastic reactions after salicylsalicylic acid; and urticarial and bronchospastic reactions after choline magnesium trisalicylate. Non-acetylated salicylates have been recommended for use in aspirin- and/or tartrazine-sensitive patients. The results of sensitivity studies of our patient indicates that such patients may also be sensitive to non-acetylated salicylates.
D S Chudwin; M Strub; H E Golden; C Frey; G W Richmond; A T Luskin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of allergy     Volume:  57     ISSN:  0003-4738     ISO Abbreviation:  Ann Allergy     Publication Date:  1986 Aug 
Date Detail:
Created Date:  1986-09-17     Completed Date:  1986-09-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372346     Medline TA:  Ann Allergy     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  133-4     Citation Subset:  IM    
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MeSH Terms
Albuterol / therapeutic use
Arthritis, Rheumatoid / drug therapy*
Asthma / drug therapy*
Bronchial Spasm / chemically induced,  drug therapy
Choline / adverse effects,  analogs & derivatives
Drug Combinations / adverse effects
Drug Hypersensitivity / etiology*
Middle Aged
Nasal Polyps / drug therapy*
Salicylates / adverse effects*
Salicylic Acids / adverse effects
Tartrazine / adverse effects
Urticaria / chemically induced
Reg. No./Substance:
0/Drug Combinations; 0/Salicylates; 0/Salicylic Acids; 18559-94-9/Albuterol; 1934-21-0/Tartrazine; 2016-36-6/choline salicylate; 552-94-3/salicylsalicylic acid; 62-49-7/Choline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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