Document Detail


Sensitivity and specificity of the tilt table test in young patients with unexplained syncope.
MedLine Citation:
PMID:  7681189     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The usefulness of the head-up tilt testing (HUT) has been previously addressed in diagnosing vasovagal neuroregulatory syncope in the teenage population. However, data concerning sensitivity and specificity is deficient due to the lack of control groups. We compared the response to HUT in young patients referred because of syncope or near syncope (n = 44, mean age 16 +/- 3 years SD) to healthy young volunteers with a normal physical examination and no previous history of syncope (n = 18, mean age 16 +/- 2 years) and to determine the sensitivity and specificity of HUT. The graded tilt protocol was performed at 15 degrees, 30 degrees, and 45 degrees (each for 2 min), and then 60 degrees for 20 minutes. Cuff blood pressure was measured every minute and lead II ECG was continuously monitored. Results: 25 of the 44 patients (57%) developed a vasovagal response or became symptomatic after 13.8 +/- 5.7 minutes of HUT. Three of the 18 volunteers (17%) had a vasovagal response and became symptomatic after 9 +/- 3 minutes of HUT. There was no statistical difference among the four groups (with and without tilt induced vasovagal response) in terms of age and baseline hemodynamic data. The sensitivity of 20 minutes HUT was 57% and its specificity was 83%. The presyncopal hemodynamic response in patients with history of syncope that was characterized by a significant decrease in systolic blood pressure and lack of increase of diastolic blood pressure as compared with baseline and with other groups.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
F M Fouad; S Sitthisook; G Vanerio; J Maloney; M Okabe; F Jaeger; M Schluchter; J D Maloney
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  16     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-04-22     Completed Date:  1993-04-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  394-400     Citation Subset:  IM; S    
Affiliation:
Department of Heart and Hypertension, Cleveland Clinic Foundation, Ohio.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Bradycardia / diagnosis,  etiology
Female
Hemodynamics / physiology
Humans
Hypotension, Orthostatic / complications,  diagnosis*
Male
Posture / physiology
Sensitivity and Specificity
Syncope / etiology*
Syndrome
Grant Support
ID/Acronym/Agency:
HL33713/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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