Document Detail


Sensitivity and specificity of programmed atrial stimulation for induction of supraventricular tachycardias.
MedLine Citation:
PMID:  3289808     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The sensitivity and specificity of two programmed atrial stimulation protocols were studied in 92 consecutive patients undergoing electrophysiologic studies both with (35 patients) and without (57 patients) clinical supraventricular arrhythmias. Protocol I (P I) consisted of incremental atrial pacing to 2:1 atrioventricular (AV) block and a single atrial extrastimulus scanned by 10 ms decrements through diastole to the atrial effective refractory period at a single drive-cycle length. Protocol II (P II) included a second atrial extrastimulus scanned by 10 ms decrements through diastole at a single drive-cycle length with the first extrastimulus set 20 ms from the atrial effective refractory period. Rapid atrial pacing at cycle lengths of 350, 300, and 250 ms was then performed with P II. P I was employed in all patients while P II was studied in the final 48 patients only. Of the 35 patients with clinical atrial arrhythmias, 26 (74%) of their arrhythmias were induced with either P I (18/35; sensitivity = 51%) and/or P II (12/17; sensitivity = 71%). Of the 57 patients without clinical atrial arrhythmias (control group), atrial arrhythmias were induced in 11 (19%), 3 with P I (specificity 95%, 54/57) and 8 with P II (specificity 74%, 23/31). The sensitivity of P II was higher (71%), but its specificity was lower (74%) than P I (51% and 95%, respectively; p less than 0.05). The positive predictive value of P II was lower (60%) than that of P I (86%) (p less than 0.05), but the negative predictive value (82%) and predictive accuracy (73%) were comparable to those of P I (76% and 78%, respectively).(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
A S Manolis; J Cameron; T Deering; E H Han; N A Estes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical cardiology     Volume:  11     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-07-29     Completed Date:  1988-07-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  307-10     Citation Subset:  IM    
Affiliation:
Department of Medicine, Tufts/New England Medical Center Hospital, Boston, Massachusetts.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Arrhythmias, Cardiac / diagnosis
Cardiac Pacing, Artificial / methods*
Child
Child, Preschool
Female
Heart Atria / physiopathology*
Humans
Male
Middle Aged
Sensitivity and Specificity
Tachycardia, Supraventricular / etiology,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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