Document Detail


Sensitivity of MEG and EEG to source orientation.
MedLine Citation:
PMID:  20640882     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An important difference between magnetoencephalography (MEG) and electroencephalography (EEG) is that MEG is insensitive to radially oriented sources. We quantified computationally the dependency of MEG and EEG on the source orientation using a forward model with realistic tissue boundaries. Similar to the simpler case of a spherical head model, in which MEG cannot see radial sources at all, for most cortical locations there was a source orientation to which MEG was insensitive. The median value for the ratio of the signal magnitude for the source orientation of the lowest and the highest sensitivity was 0.06 for MEG and 0.63 for EEG. The difference in the sensitivity to the source orientation is expected to contribute to systematic differences in the signal-to-noise ratio between MEG and EEG.
Authors:
Seppo P Ahlfors; Jooman Han; John W Belliveau; Matti S Hämäläinen
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-07-18
Journal Detail:
Title:  Brain topography     Volume:  23     ISSN:  1573-6792     ISO Abbreviation:  Brain Topogr     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-04     Completed Date:  2010-11-22     Revised Date:  2011-06-16    
Medline Journal Info:
Nlm Unique ID:  8903034     Medline TA:  Brain Topogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  227-32     Citation Subset:  IM    
Affiliation:
MGH/HST Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, 149 13th Street, Rm 2301, Charlestown, MA 02129, USA. seppo@nmr.mgh.harvard.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain Mapping*
Cerebral Cortex / physiology*
Electroencephalography*
Humans
Magnetoencephalography*
Male
Models, Neurological
Orientation*
Sensitivity and Specificity
Signal Processing, Computer-Assisted
Grant Support
ID/Acronym/Agency:
HD040712/HD/NICHD NIH HHS; NS037462/NS/NINDS NIH HHS; NS057500/NS/NINDS NIH HHS; P41RR14075/RR/NCRR NIH HHS; R01 HD040712-08/HD/NICHD NIH HHS
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