Document Detail


Sensitivity of Escherichia coli to cephaloridine at different growth rates.
MedLine Citation:
PMID:  35527     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Steady-state populations of Escherichia coli B/r were treated with cephaloridine at minimal inhibitory concentrations. The antibiotic sensitivity of the cells and the localization of spheroplast emergence along the cell surface were examined as a function of cell length and growth rate. In fast-growing populations (greater than 1 division per h) the sites of cephaloridine interaction occurred preferentially at the cell pole in the smaller cells and at the cell center in dividing cells. At decreasing growth rates the cells became more resistant to cephaloridine, and a gradual shift from the cell pole toward the cell center was observed for the sphere position. A similar growth rate-dependent change in localization was found for sucrose-induced plasmolysis vacuoles.
Authors:
E Mathys; A Van Gool
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of bacteriology     Volume:  138     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1979 May 
Date Detail:
Created Date:  1979-07-28     Completed Date:  1979-07-28     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  642-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cell Division
Cell Wall / drug effects
Cephaloridine / pharmacology*
Culture Media
Drug Resistance, Microbial
Escherichia coli / cytology,  drug effects*,  growth & development
Hydrogen-Ion Concentration
Spheroplasts / isolation & purification
Vacuoles / drug effects
Chemical
Reg. No./Substance:
0/Culture Media; 50-59-9/Cephaloridine
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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