| Sensitivity of the Doppler rate of pressure rise to changes in the inotropic state: an experimental comparison with invasively obtained dP/dt. | |
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MedLine Citation:
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PMID: 11916605 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To investigate the sensitivity of the rate of pressure rise obtained by Doppler to changes in the inotropic state by comparing it to simultaneous invasive measurements of dP/dt under different conditions of contractility. METHODS AND RESULTS: Mitral regurgitation was provoked in five pigs, and simultaneous measurements of dP/dt and the Doppler-estimated rate of pressure rise were made with a micro-manometer and with continuous-wave Doppler. Changes in the inotropic state were induced by drug infusion and by ischaemia. One hundred and twenty-seven simultaneous measurements were made with a correlation coefficient between the Doppler-estimated rate of pressure rise and dP/dt of 0.85 (P<0.001). Sensitivity to inotropic changes was estimated as the percentage change of each parameter in each condition of contractility, and showed that the Doppler-estimated rate of pressure rise had better sensitivity than dP/dt. CONCLUSION: The sensitivity of Doppler-estimated rate of pressure rise to changes in the inotropic state is greater than that of dP/dt. The correlation between the rate of pressure rise obtained by Doppler and dP/dt is maintained even in extreme conditions of contractility. Therefore, the rate of pressure rise can be considered a good parameter to assess linear changes of contractility. |
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Authors:
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A García-Lledó; J L Moya; J Balaguer; E Asín |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology Volume: 1 ISSN: 1525-2167 ISO Abbreviation: Eur J Echocardiogr Publication Date: 2000 Dec |
Date Detail:
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Created Date: 2002-03-27 Completed Date: 2002-05-01 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100890618 Medline TA: Eur J Echocardiogr Country: England |
Other Details:
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Languages: eng Pagination: 271-6 Citation Subset: IM |
Affiliation:
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Department of Cardiology, General Hospital of Guadalajara, Spain. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure / physiology* Disease Models, Animal Echocardiography, Doppler, Color* Heart Atria / physiopathology, ultrasonography Mitral Valve Insufficiency / physiopathology, ultrasonography Models, Cardiovascular Models, Theoretical Multivariate Analysis Myocardial Contraction / physiology* Sensitivity and Specificity Statistics as Topic Swine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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