Document Detail

The sensitivity of the 2- to 4-month-old human infant accommodation system.
MedLine Citation:
PMID:  20042651     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The goal of this study was to compare objectively the sensitivity of the accommodation system in human infants and adults under binocular and monocular viewing conditions.
METHODS: Full-term infants from 2 to 4 months of age and pre-presbyopic adults were presented with a high-contrast cartoon stimulus moving sinusoidally in diopters around a mean position of 2 D (50 cm). Three stimulus amplitudes were used in one trial (0.25, 0.50, and 0.75 D), with unpredictable stimulus motion during each amplitude change. Eccentric photorefraction was used to record accommodative responses at 25 Hz. The stimulus was made monocular by placing an infrared filter over the right eye, to block visible light but pass the near-infrared wavelength of the photorefractor and allow responses to be recorded from both eyes.
RESULTS: Fourier analysis was used to determine the accommodative response at the frequency of the stimulus. Significant signal-to-noise ratios indicated that, on average, the 2- to 4-month-old infants generated an accommodative response to at least the 0.75 D amplitude monocular stimulus and the 0.75 and 0.50 D binocular stimuli. Adults responded to the 0.25 D amplitude both binocularly and monocularly.
CONCLUSIONS: In infants 2 to 4 months of age, the developing visual system compensates for small changes in defocus relative to the typical amounts of hyperopic refractive error found at that age.
Jingyun Wang; T Rowan Candy
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural     Date:  2009-12-30
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  51     ISSN:  1552-5783     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-20     Completed Date:  2010-06-11     Revised Date:  2014-09-15    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3309-17     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Accommodation, Ocular / physiology*
Fourier Analysis
Myopia / physiopathology
Refraction, Ocular / physiology
Retina / physiology
Sensitivity and Specificity
Vision, Binocular / physiology
Vision, Monocular / physiology
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Presbyopic spectacle coverage, willingness to pay for near correction, and the impact of correcting ...
Next Document:  In search of the identity of the XAP-1 antigen: a protein localized to cone outer segments.