| Sensitive spectrophotometric method for quantitation of guaifenesin and dropropizine in their dosage forms. | |
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MedLine Citation:
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PMID: 20671996 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Guaifenesin and dropropizine were analyzed through oxidation with periodic acid to give formaldehyde which was allowed to condense with 4-Amino-5-hydrazino-4H [1,2,4]-triazole-3-thiol (AHTT). The condensation product was further oxidized to yield a purple colored compound with maximum absorption at 550 nm. Beer's law was obeyed in the range of 5-45 mug mL(-1) for guaifenesin and 10-80 mug mL(-1) for dropropizine. Both drugs were also successfully determined in their dosage forms. |
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Authors:
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Ola M Abdallah |
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Publication Detail:
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Type: Journal Article Date: 2010-06-29 |
Journal Detail:
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Title: International journal of analytical chemistry Volume: 2010 ISSN: 1687-8779 ISO Abbreviation: Int J Anal Chem Publication Date: 2010 |
Date Detail:
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Created Date: 2010-07-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101519424 Medline TA: Int J Anal Chem Country: Egypt |
Other Details:
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Languages: eng Pagination: 704564 Citation Subset: - |
Affiliation:
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Faculty of Pharmacy, October University for Modern Sciences and Arts, El Wahat Road, 6th October City, Egypt. |
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