| Sensing applications of synthetic transport systems. | |
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MedLine Citation:
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PMID: 23154531 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This feature article offers a comprehensive account of a decade of research devoted to the combination of the grand sensing principles with synthetic transport systems that act in lipid bilayers. Differential sensing, that is pattern generation and pattern recognition, is exemplified with an artificial nose. The aptamer version of immunosensing is realized with sticky-end polymers of DNA double helices for both signal generation and signal transduction. Biosensing, that is the use of enzymes for signal generation, is exemplified first with an artificial tongue and then expanded to analytes such as cholesterol, phytate or polyphenols. Enjoyable also for the general reader, we hope that this account will inspire supramolecular organic as well as analytical, physical and biological chemists. |
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Authors:
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Toshihide Takeuchi; Stefan Matile |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-16 |
Journal Detail:
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Title: Chemical communications (Cambridge, England) Volume: - ISSN: 1364-548X ISO Abbreviation: Chem. Commun. (Camb.) Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610838 Medline TA: Chem Commun (Camb) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Organic Chemistry, University of Geneva, Geneva, Switzerland. stefan.matile@unige.ch. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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