Document Detail

Semipermeable dressing and transepidermal water loss in premature infants.
MedLine Citation:
PMID:  2388784     Owner:  NLM     Status:  MEDLINE    
Within the first days of life, 10 infants, of 32 weeks' gestational age or less, began 2 weeks of treatment with a semipermeable wound dressing over a small area of skin. The effects of the dressing on transepidermal water loss and cutaneous microflora were evaluated. Transepidermal water loss from the semipermeable dressing-treated skin was significantly less than that from the untreated skin immediately after placement of the dressing (8.1 +/- 1.8 g/m2.h-1 vs 17.7 +/- 3.5 g/m2.h-1, P less than .0001). The normal accelerated skin maturation process that occurs in these infants continued beneath the semipermeable dressing. The number of gram-negative bacilli or other bacteria did not increase beneath the semipermeable dressing beyond that seen on the untreated site. Malassezia furfur was found only on the control site, never beneath the semipermeable dressing. According to results of this preliminary study, a semipermeable dressing can be safely used in premature infants and the use of a semipermeable dressing may decrease the excessive transepidermal water loss associated with prematurity.
H J Vernon; A T Lane; L J Wischerath; J M Davis; M A Menegus
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatrics     Volume:  86     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-09-27     Completed Date:  1990-09-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  357-62     Citation Subset:  AIM; IM    
Department of Dermatology, University of Rochester School of Medicine and Dentistry, New York.
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MeSH Terms
Bacteria / isolation & purification
Epidermis / physiology*
Gestational Age
Infant, Newborn
Infant, Premature / physiology*
Skin / microbiology
Time Factors
Water Loss, Insensible / physiology*
Reg. No./Substance:

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