| Semiconserved regulation of mesendoderm differentiation by microRNAs. | |
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MedLine Citation:
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PMID: 19386256 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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MicroRNAs are known to play important roles in many different processes. However, their roles in shaping the early steps in embryogenesis have remained largely hidden. In this issue of Developmental Cell, Rosa et al. show that the miR-430/427/302 family of microRNAs has a distinct effect on Nodal signaling, affecting mesendoderm differentiation in Xenopus embryos and human embryonic cell lines. |
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Authors:
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René F Ketting |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Developmental cell Volume: 16 ISSN: 1878-1551 ISO Abbreviation: Dev. Cell Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-04-23 Completed Date: 2009-05-15 Revised Date: 2009-05-22 |
Medline Journal Info:
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Nlm Unique ID: 101120028 Medline TA: Dev Cell Country: United States |
Other Details:
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Languages: eng Pagination: 487-8 Citation Subset: IM |
Affiliation:
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Hubrecht Institute-KNAW and University Medical Centre Utrecht, Utrecht, The Netherlands. r.ketting@hubrecht.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Differentiation* Cell Lineage / drug effects Endoderm / cytology*, drug effects, embryology, metabolism Humans Mesoderm / cytology*, drug effects, embryology, metabolism MicroRNAs / genetics, metabolism* Oligonucleotides, Antisense / pharmacology Species Specificity Xenopus laevis / embryology, genetics |
| Chemical | |
Reg. No./Substance:
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0/MIRN302 microRNA, human; 0/MicroRNAs; 0/Oligonucleotides, Antisense |
| Comments/Corrections | |
Comment On:
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Dev Cell. 2009 Apr;16(4):517-27
[PMID:
19386261
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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