Document Detail


Semi-synthetic approaches to novel penicillins.
MedLine Citation:
PMID:  1891804     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The first part of this account of the discovery of penicillin, published in last month's issue of TIBS, concluded with the detection of 6-beta-amino-penicillanic acid (6-APA), the nucleus of the penicillin structure. The exploitation of 6-APA led to the preparation of a range of clinically important semi-synthetic penicillins, which is described in this article.
Authors:
J H Nayler
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Trends in biochemical sciences     Volume:  16     ISSN:  0968-0004     ISO Abbreviation:  Trends Biochem. Sci.     Publication Date:  1991 Jun 
Date Detail:
Created Date:  1991-10-15     Completed Date:  1991-10-15     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7610674     Medline TA:  Trends Biochem Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  234-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Penicillins / chemical synthesis*
Chemical
Reg. No./Substance:
0/Penicillins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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