Document Detail

Semen zinc levels in infertile and postvasectomy patients and patients with prostatitis.
MedLine Citation:
PMID:  1183629     Owner:  NLM     Status:  MEDLINE    
The semen zinc levels were determined in 18 volunteers, 132 patients postvasectomy, and in 19 patients with prostatitis. The mean values for semen zinc were the same in the volunteers and postvasectomy patients. However, the mean zinc concentration in the volunteers and postvasectomy patients was significantly different from that of the patients with prostatitis. When a group of 12 patients with prostatitis was given supplementary zinc sulfate, the levels of semen zinc rose dramatically and were significantly different from those before treatment. As part of an infertility evaluation, 153 specimens from 72 men who had not fathered a child were examined. A complete semen analysis of each specimen was made, including the semen zinc concentration. The specimens were separated into four arbitrary groups with differing fertility potential. The groups were organized by sperm counts (less than 20 million sperm/ml, 20 to 60 million sperm/ml, 60 to 100 million sperm/ml, and greater than 100 million sperm/ml). There was a trend toward increasing zinc concentrations in the groups with increasing fertility potential. Eleven patients with oligospermia and low semen zinc levels were given supplementary zinc sulfate, 80 mg three times/day for 6 months to 1 year. The parameters of the semen analysis improved in all categories. There were three pregnancies during the period of treatment.
J L Marmar; S Katz; D E Praiss; T J DeBenedictis
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  26     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1975 Nov 
Date Detail:
Created Date:  1976-02-02     Completed Date:  1976-02-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1057-63     Citation Subset:  IM    
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MeSH Terms
Cell Count
Infertility, Male / drug therapy,  metabolism*
Prostatitis / metabolism*
Semen / analysis*
Sperm Motility
Spermatozoa / cytology
Zinc / analysis,  metabolism*,  therapeutic use
Reg. No./Substance:

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