Document Detail


Self-reported exposure to pesticides and radiation related to pregnancy outcome--results from National Natality and Fetal Mortality Surveys.
MedLine Citation:
PMID:  2508175     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although fetal development is known to be sensitive to environmental agents, relatively little epidemiologic research has addressed this concern. Effects on pregnancy outcome of self-reported parental exposure to pesticides and to radiation were examined using data from the National Natality and Fetal Mortality Surveys, large national probability samples of live births and stillbirths occurring in 1980. In case-control analyses, maternal exposure to pesticides at home or work was associated with increased risk of stillbirth (odds ratios (ORs) = 1.5-1.6). Paternal pesticide exposure was associated with stillbirth (ORs = 1.2-1.4) and delivery of small-for-gestational-age infants (ORs = 1.4-2.0). A small increased risk of stillbirth (OR = 1.3) was found in relation to either parent's reported exposure to radiation. In spite of limitations in the quality of exposure data and the possibility of biased recall related to pregnancy outcome, associations of reported pesticide exposure to either parent with risk of stillbirth and small-for-gestational-age infants warrant further evaluation.
Authors:
D A Savitz; E A Whelan; R C Kleckner
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Public health reports (Washington, D.C. : 1974)     Volume:  104     ISSN:  0033-3549     ISO Abbreviation:  Public Health Rep     Publication Date:    1989 Sep-Oct
Date Detail:
Created Date:  1989-11-01     Completed Date:  1989-11-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9716844     Medline TA:  Public Health Rep     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  473-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599.
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MeSH Terms
Descriptor/Qualifier:
Case-Control Studies
Embryonic and Fetal Development / drug effects,  radiation effects*
Environmental Exposure*
Female
Fetal Death / etiology
Humans
Interviews as Topic
Pesticides*
Pregnancy
Pregnancy Outcome*
Questionnaires
Radioactive Pollutants*
United States
Chemical
Reg. No./Substance:
0/Pesticides; 0/Radioactive Pollutants
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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