Document Detail

Self pregnancy testing in an urban family planning clinic: promising results for a new approach to contraceptive follow-up.
MedLine Citation:
PMID:  18082665     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Immediate initiation of depo-medroxyprogesterone acetate (DMPA) increases continuation and decreases pregnancies compared to conventional (next menstrual period) initiation. A drawback is the need to return in 4 weeks for a repeat pregnancy test to identify any pregnancy that was too early to diagnose on the day of injection. If women can perform home pregnancy tests (HPTs) to detect human chorionic gonadotropin (hCG) in urine, the need for this follow-up visit may be eliminated. This study assesses whether women can perform their own HPT. STUDY DESIGN: This is a single-visit observational trial of an HPT kit. Subjects recruited from a waiting room in an urban family planning clinic received an HPT kit with standard instructions to use immediately. Subjects and a research assistant each interpreted the test. Their results were then compared to a standard cassette type test for detection of hCG performed by clinic staff. kappa was calculated to assess the level of agreement. RESULTS: Three hundred ten subjects enrolled. They were young (mean age, 25.2 years), mostly Hispanic (91%) women. A change in the font and explicitness of the instructions decreased the incidence of invalid tests from 12.7% to 4.8%. The subject and research assistant's interpretation of the test had a high level of agreement, kappa=0.95 [95% confidence interval (CI), 0.92-0.99]. There was also a high level of agreement between the subjects' results and the standard test, kappa=0.88 (95% CI, 0.82-0.95). CONCLUSIONS: Women presenting for pregnancy testing at an urban clinic are able to perform HPTs with a high level of accuracy. The appearance of the instructions influenced the incidence of false-negative and invalid tests. Home pregnancy tests may be useful in follow-up protocols when immediate initiation of DMPA is employed.
Christopher M Estes; Jahanett Ramirez; Jahanett Ramierez; Lorraine Tiezzi; Carolyn Westhoff
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-11-26
Journal Detail:
Title:  Contraception     Volume:  77     ISSN:  0010-7824     ISO Abbreviation:  Contraception     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-12-17     Completed Date:  2008-03-25     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0234361     Medline TA:  Contraception     Country:  United States    
Other Details:
Languages:  eng     Pagination:  40-3     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Columbia University, New York, NY 10032, USA.
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MeSH Terms
Ambulatory Care Facilities
Cohort Studies
Contraceptive Agents, Female / therapeutic use*
False Negative Reactions
Medroxyprogesterone Acetate / therapeutic use*
Patient Education as Topic
Pregnancy Tests / methods*,  standards
Self Care*
Urban Population
Reg. No./Substance:
0/Contraceptive Agents, Female; 71-58-9/Medroxyprogesterone Acetate
Erratum In:
Contraception. 2008 Jun;77(6):467
Note: Ramierez, Jahanett [corrected to Ramirez, Jahanett]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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