Document Detail


Self-organized and highly ordered domain structures within swarms of Myxococcus xanthus.
MedLine Citation:
PMID:  16421928     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Coordinated group movement (swarming) is a key aspect of Myxococcus xanthus' social behavior. Here we report observation of domain structures formed by multiple cells within large three-dimensional swarming groups grown on amorphous glass substrates, using the atomic force microscope (AFM). Novel analyses revealed that 90% of the wild type swarms displayed some form of preferential cell alignment. In contrast, cells with mutations in the social and adventurous motility systems displayed a distinct lack of cell alignment. Video microscopy observations of domain features of in vivo swarming M. xanthus cells were also consistent with the AFM data. The results presented here reveal that unique domain formation within swarms of wild type cells is a biologically driven process requiring the social and adventurous motility systems and is not a statistical phenomenon or thermodynamic process arising from liquid crystal behavior.
Authors:
Andrew E Pelling; Yinuo Li; Sarah E Cross; Schryl Castaneda; Wenyuan Shi; James K Gimzewski
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Cell motility and the cytoskeleton     Volume:  63     ISSN:  0886-1544     ISO Abbreviation:  Cell Motil. Cytoskeleton     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-02-23     Completed Date:  2006-05-08     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8605339     Medline TA:  Cell Motil Cytoskeleton     Country:  United States    
Other Details:
Languages:  eng     Pagination:  141-8     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2006 Wiley-Liss, Inc.
Affiliation:
Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA. a.pelling@ucl.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Microscopy, Atomic Force
Microscopy, Video
Myxococcus xanthus / cytology*,  genetics
Social Behavior*
Time Factors
Grant Support
ID/Acronym/Agency:
GM54666/GM/NIGMS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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