| Self or nonself? That is the question: sensing of cytomegalovirus infection by innate immune receptors. | |
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MedLine Citation:
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PMID: 20882286 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Cytomegaloviruses (CMV) are ubiquitous, opportunistic DNA viruses that have mastered the art of immune evasion through their ability to mimic host proteins or to inhibit antiviral responses. The study of the host response against CMV infection has illuminated many facets of the complex interaction between host and pathogen. Here, we review evidence derived from the animal models and human studies that supports the central role played by innate immune receptors in the recognition of virus infection and their participation in the many layers of defense. |
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Authors:
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Michal Pyzik; Eve-Marie Gendron-Pontbriand; Nassima Fodil-Cornu; Silvia M Vidal |
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Publication Detail:
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Type: Journal Article Date: 2010-09-30 |
Journal Detail:
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Title: Mammalian genome : official journal of the International Mammalian Genome Society Volume: 22 ISSN: 1432-1777 ISO Abbreviation: Mamm. Genome Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9100916 Medline TA: Mamm Genome Country: United States |
Other Details:
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Languages: eng Pagination: 6-18 Citation Subset: IM |
Affiliation:
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Department of Human Genetics and Centre for the Study of Host Resistance, McGill University, Montreal, QC, H3G 0B1, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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